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| Section | Weight | Objectives |
|---|---|---|
| Patient-Centered Pharmacotherapy | 55% | - Monitoring and Follow-Up
|
| Drug Information and Evidence-Based Medicine | 25% | - Literature Evaluation
|
| System-Based Standards and Population-Based Pharmacotherapy | 20% | - Population Health and Public Health
|
1. Two antihypertensive regimens have been compared in 50 patients with mild hypertension.
Treatment A decreased mean diastolic blood pressure to 81 mm Hg, and Treatment B decreased it to 85mm Hg (p = 0.08, a priori critical a = 0.05). The most reasonable interpretation of these results is that the difference between treatments is:
A) Statistically but not clinically significant.
B) Neither statistically nor clinically significant.
C) Clinically but not statistically significant.
D) Statistically and clinically significant.
2. Before initiating thrombolytic therapy in a 58 year old patient who has just sustained an acute anterior MI, which of the following must be ascertained?
A) Medical history, current medications, and serum electrolytes
B) Medical history, vital sign, duration of chest pain, and current medications
C) aPTT, serum electrolytes and duration of chest pain
D) Vital signs, current medications and cardiac enzymes
3. A 70-year-old man has completed a 14-day course of sulfamethoxazole/trimethoprim for Escherichia coli cystourethritis. The patient has a Foley catheter. A urine culture obtained 24 hours after the last antibiotic dose shows Candida albicans > 10x3 cfu/mL, RBC > 100 cells/hpf, and WBC = 10-20 cells/hpf. The patient is asymptomatic. What is the most appropriate management?
A) Amphotericin bladder irrigation for 5-10 days
B) No anti-infective needed
C) Posaconazole orally daily for 5-10 days
D) Fluconazole orally daily for 5-10 days
4. A 21-year-old patient with leukemia is admitted to the hospital with a temperature of 38.9°C and a nonproductive cough 8 days after induction chemotherapy completion. Laboratory tests show a WBC count of 1,000 cells/ul (10% segmented neutrophils, 0% bands, and 90% lymphocytes) and a platelet count of 60,000 cells/uL. Chest X-ray reveals a small left lower lobe infiltrate. Blood, urine, and sputum cultures are obtained. What should be the recommendation for initial management?
A) Hold antibiotics until Culture results are available.
B) Initiate amphotericin, ceftazidime, and gentamicin.
C) Initiate fluconazole, vancomycin, and imipenem.
D) Initiate cefepime, Vancomycin, and tobramycin.
5. Which of the following quality performance measures would be most appropriate to evaluate in relation to anticoagulation management in the outpatient setting?
A) Bleeding and thromboembolic complication rates
B) Medication adherence rates
C) Percentage of time in therapeutic range
D) Percentage of extremely high INRS
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: D | Question # 3 Answer: B | Question # 4 Answer: D | Question # 5 Answer: B |
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