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USMLE USMLE Exam : United States Medical Licensing Examination

USMLE actual test
  • Exam Code: USMLE
  • Exam Name: United States Medical Licensing Examination
  • Updated: Sep 12, 2026
  • Q & A: 400 Questions and Answers
  • PDF Demo
  • PC Test Engine
  • Online Test Engine
  • Total Price: $59.99  

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USMLE Step 3 is open to candidates who already hold their USMLE Step 1 and Step 2 certificates. Step 3 is a two-day exam that assesses whether candidates are able apply medical knowledge and understanding of biomedical and clinical science essential to unsupervised medical practice. This is the final USMLE exam which leads to the license to practice medicine without supervision - the ultimate goal of medical students and professionals willing to practice medicine in the United States. Step 3 represents the final assessment of physicians assuming independent responsibility for delivering general medical care.

USMLE Step 2 is a one-day (8 hours) exam. Similar to the Step 1, the test items are divided into blocks, and test item formats vary within each block, with the total number of exam questions equaling to 355.

Reference: http://www.usmle.org/step-1/#question-formats

USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Topic 1: General Principles- Foundational Medical Sciences
  • 1. Physiology
  • 2. Immunology
  • 3. Genetics
  • 4. Pathology
  • 5. Biochemistry
  • 6. Behavioral Sciences
  • 7. Microbiology
  • 8. Pharmacology
Topic 2: Cardiovascular System- Cardiac and Vascular Disorders
  • 1. Vascular Pathology
  • 2. Heart Disease
Topic 3: Hematopoietic and Lymphoreticular Systems- Blood and Immune Disorders
  • 1. Coagulation Disorders
  • 2. Leukemias and Lymphomas
  • 3. Anemias
Topic 4: Multisystem Processes and Disorders- Systemic Conditions
  • 1. Infectious Diseases
  • 2. Nutrition
  • 3. Neoplasia
Topic 5: Gastrointestinal System- Digestive System Disorders
  • 1. Liver Disease
  • 2. Gastrointestinal Pathology
Topic 6: Central and Peripheral Nervous Systems- Neurologic Disorders
  • 1. Neurologic Diseases
  • 2. Neuroanatomy
  • 3. Neuropathology
Topic 7: Human Development- Growth and Development
  • 1. Developmental Abnormalities
  • 2. Embryology
Topic 8: Renal and Urinary System- Kidney and Urinary Disorders
  • 1. Renal Pathology
  • 2. Renal Physiology
Topic 9: Musculoskeletal System- Bones, Joints, and Muscles
  • 1. Rheumatologic Diseases
  • 2. Orthopedic Disorders
Topic 10: Reproductive System- Male and Female Reproductive Health
  • 1. Reproductive Disorders
  • 2. Reproductive Physiology
Topic 11: Respiratory System- Pulmonary Medicine
  • 1. Airway Disorders
  • 2. Lung Diseases
Topic 12: Endocrine System- Hormonal Regulation and Disease
  • 1. Thyroid Disorders
  • 2. Pituitary Disorders
  • 3. Adrenal Disorders
Topic 13: Skin and Related Connective Tissue- Dermatologic Conditions
  • 1. Skin Neoplasms
  • 2. Inflammatory Skin Disorders

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